- What are ketones?
- Why are ketones, though toxic, today the basis of many “extreme” slimming diets?
- Theory: effectiveness and mechanism for the action of the raspberry ketone integrators
- Method of use and side effects
Raspberry ketone is a new ingredient contained in some supplements for the disposal of body fat. This is an extract from raspberry fruit (raspberry). Which is primarily industrial (to include costs, otherwise exorbitant) and added in concentrations up to 450 times higher than those contained in a portion of its fresh fruit. Raspberry ketone is, therefore, a thermogenic active substance used in grease supplements.
What are ketones?
Ketones (CnH2nO) are molecules consisting of a carbon group (C=O) and two alkyl radials (R). Ketones are derived from the oxidation of secondary alcohols by oxidoriduction and, in the human body, represent the “waste” of energy production (although some tissues can reuse them). When the blood concentrations of ketones (or ketonic groups) are excessive (due to a diet free or too low of carbohydrates). They result in toxic cell-level action (especially for the nervous and renal systems) because their disposal is not effective enough to compensate for their accumulation.
Why are ketones, though toxic, today the basis of many “extreme” slimming diets?
The slimming diets causing the ketone to increase are used in slimming mode because these catabolites inhibit the nervous stimulation of appetite. On the other hand, one question spontaneously arises: as potentially harmful substances, what consequences could arise in the association of a ketogenic diet with the integration of raspberry ketone? Honestly, I wouldn’t try them on my skin.
Theory: effectiveness and mechanism for the action of the raspberry ketone integrators
The integration of ketones with raspberry ketone is recommended (by the company that markets it) in weight-loss diets, such as catering and grease. And non-pharmacological treatment of low-elastic fat and bald skins.
According to US doctor Dr. Mehmed Oz, raspberry ketone can reduce fatty tissue due to the body’s overall metabolic increase. This mechanism lies at the base of all other thermogenic supplements.
Studies have observed the metabolic effects of raspberry ketone on both the rat and the human; the researchers, therefore, pointed out a correlation between the intake of raspberry ketone and:
- Increase of adiponectin (Raspberry ketone augmentation both lipolysis and fatty acid oxidation in 3T3-L1 adipocytes; Anti-obese action of raspberry ketone – PUBMED)
- Rise in noradrenaline (catecholamine – a hormone which also promotes lipolysis)
- Effect of topical application of raspberry ketone on dermal production of insulin-like growth factor-I in mice and hair growth and skin elasticity (PUBMED).
- The stimulus of sustained growth in those affected by alopecia.
Therefore, it was assumed that, in addition to favoring the weight decrease. The hormone impact of raspberry ketone could also significantly benefit individuals with reduced glucosidic tolerance (including type 2 diabetes) or metabolic changes of various kinds.
In short, it is possible that the Raspberry ketone supplement, inserted in the context of a low-calorie diet, could facilitate the reduction of adipose tissue and thus the generalized slimming.
Method of use and side effects
At present, there is insufficient information to establish a maximum intake dose; it is indeed a food supplement and not a drug. However, by acting in a stimulative manner on catecholamines (similar to capsicin, symmetry, caffeine, etc.), excessive doses of raspberry ketone may induce nervousness, sleep alterations, and all the side effects associated with the abuse of thermogenic supplements (which are significantly aggravated by “discussions” affordable low-carb energy).
Dosages of about 200 mg/day of Raspberry ketone (non-pure ketone) integrators, split into two 100 mg intakes, could be effective and considered safe.
NOTE: The ketone supplement raspberry ketone is unrecommended for pregnancy, breastfeeding, and development due to a lack of specific information.